01 - Combine sliced strawberries and sugar in a medium bowl. Toss thoroughly and let stand for 20 minutes to allow juices to develop.
02 - Preheat oven to 425°F. Line a baking sheet with parchment paper.
03 - Whisk together flour, sugar, baking powder, and salt in a large bowl until well combined.
04 - Add cold cubed butter to flour mixture. Cut in using pastry blender or fingertips until mixture resembles coarse crumbs.
05 - Stir in buttermilk and vanilla extract just until dough comes together. Avoid overmixing.
06 - Turn dough onto lightly floured surface. Pat into 1-inch-thick rectangle. Cut 6 biscuits using 2½-inch round cutter, re-rolling scraps as needed.
07 - Place biscuits on prepared baking sheet. Brush tops with melted butter. Bake for 16–18 minutes until golden brown. Cool on wire rack.
08 - In chilled mixing bowl, beat cold cream, powdered sugar, and vanilla with hand mixer or whisk until soft peaks form.
09 - Split biscuits horizontally. Layer bottoms with macerated strawberries and juices, top with whipped cream, then add biscuit tops. Garnish with additional berries and cream if desired.